Two new metabolites from the mangrove endophytic fungus no. 2524

被引：30

作者：

Li, HJ

Lin, YC ^{[1
]}

Yao, JH

Vrijmoed, LLP

Jones, EBG

机构：

[1] Zhongshan Univ, Sch Chem & Chem Engn, Guangzhou 510275, Peoples R China

[2] Zhongshan Univ, Instrumental Anal & Res Ctr, Guangzhou 510275, Peoples R China

[3] City Univ Hong Kong, Dept Biol & Chem, Hong Kong, Hong Kong, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2004年 / 6卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Avicennia marina; endophytic fungus; metabolites; cyclo-(L-Phe-L-Leu(1)-L-Leu(2)-L-Leu(3)-L-Ile); (3S; 4R)-Dihydroxy-(6S)-undecyl-alpha-pyranone;

D O I：

10.1080/102860201653237

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new metabolites, the cyclo-(L-Phe-L-Leu(1)-L-Leu(2)-L-Leu(3) -L-Ile) ( 1 ) and (3 S ,4 R )-dihydroxy-(6 S )-undecyl-alpha-pyranone ( 2 ) have been produced by the endophytic fungus no. 2524 isolated from a seed of mangrove Avicennia marina in Hong Kong. The structures have been elucidated by spectra including two-dimensional NMR, ESI tandem mass spectrometry and CD. These compounds show no activity toward human cancer cell lines Bel-7402, NCI-4460 and the normal human cell lines L-02.

引用

页码：185 / 191

页数：7

共 6 条

[1]

BEECHAM AF, 1968, TETRAHEDRON LETT, P3591

[2] The metabolites of the mangrove fungus Verruculina enalia No. 2606 from a salt lake in the Bahamas [J].