Chromosome mapping of the mouse Akt2 gene and Akt2 pseudogene

被引：6

作者：

Altomare, DA

Kozak, CA

Sonoda, G

Testa, JR

机构：

[1] FOX CHASE CANC CTR,DEPT MED ONCOL,PHILADELPHIA,PA 19111

[2] NIH,BETHESDA,MD 20892

来源：

CYTOGENETICS AND CELL GENETICS | 1996年 / 74卷 / 04期

关键词：

D O I：

10.1159/000134426

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We previously reported the cloning of a murine cDNA encoding the protein-serine/threonine kinase Akt2, and we used this clone to map the Akt2 gene to mouse chromosome (MMU) 7B1 by fluorescence in situ hybridization. We now have cloned and partially sequenced a mouse Akt2 pseudogene. An analysis of two sets of multilocus crosses revealed that the Akt2 gene is closely linked to the Cyp2a locus in proximal MMU7. The Akt2 pseudogene was mapped to proximal MMU11 by both multilocus mapping and fluorescence in situ hybridization.

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页码：248 / 251

页数：4

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