Strained aromatic oligoamide macrocycles as new molecular clips

被引：147

作者：

Jiang, H

Léger, JM

Guionneau, P

Huc, I ^{[1
]}

机构：

[1] Inst Europeen Chim & Biol, 2 Rue Robert Escarpit, F-33607 Pessac, France

[2] Lab Pharmacochim, F-33076 Bordeaux, France

[3] Inst Chim Mat Condensee Bordeaux, F-33608 Pessac, France

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 17期

关键词：

D O I：

10.1021/ol0488643

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Can one join both ends of a helix? A helical aromatic oligoamide was macrocyclized into a saddle-shaped bifunctional clip molecule that self-assembles into discrete circular dodecamers in the solid state and shows great potential for binding aromatic acid guests in solution. The cyclization step requires that the helix is only partly denatured in the reaction medium.

引用

页码：2985 / 2988

页数：4

共 22 条

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