Wireless, power-free and implantable nanosystem for resistance-based biodetection

In-vivo devices and systems are extensively used in medical field to real-time detect and adjust the physiological status of human being, but supplying energy in-vivo for these devices and systems is still a great challenge. In this work, we first developed a new kind of wireless nanogenerator (WLNG) based on biocompatible BZT-BCT nanowires (NWs). It works through compressing and releasing BZT-BCT NWs/PDMS nanocomposite by a changing magnetic field in wireless non-contact mode. The maximum output voltage reaches 19 V, and the maximum output current is 1.17 mu A, which are 21.9% larger than the reported maximum output voltage 12 V and 214 times of the reported maximum 50 nA of non-contact nanogenerator. And we further integrated it with a new kind of transmitter into a wireless, power-free and implantable nanosystem for in-vivo biodetection. This nanosystem does not need any electrical power. An in-vitro changing magnetic field can be used to drive it to detect the variation of resistance invivo and wirelessly transmit the signal to the equipments in-vitro. (C) 2015 Elsevier Ltd. All rights reserved.