Use of calibrated viral load standards for group m subtypes of human immunodeficiency virus type 1 to assess the performance of viral RNA quantitation tests

被引:47
作者
Jagodzinski, LL
Wiggins, DL
McManis, JL
Emery, S
Overbaugh, J
Robb, M
Bodrug, S
Michael, NL
机构
[1] Henry M Jackson Fdn, Rockville, MD 20850 USA
[2] Walter Reed Army Inst Res, Div Retrovirol, Rockville, MD 20850 USA
[3] Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA
[4] Gen Probe Inc, San Diego, CA 92121 USA
关键词
D O I
10.1128/JCM.38.3.1247-1249.2000
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Optimal management of human immunodeficiency virus type 1 (HIV-1) disease requires accurate quantitation of viral RNA concentrations in plasma. Evidence for increasing geographic intermixing of HIV-1 subtypes makes equivalent quantitation of all subtypes essential. The performances of six quantitative viral RNA tests are described, for the first time, with calibrated viral isolates of diverse subtypes.
引用
收藏
页码:1247 / 1249
页数:3
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