Biotransformation of oleic acid into 10-hydroxy-8E-octadecenoic acid by Pseudomonas sp 42A2

被引：13

作者：

Bastida, J

de Andrés, C

Culleré, J

Busquets, M

Manresa, A ^{[1
]}

机构：

[1] Univ Barcelona, Fac Farm, Microbiol Lab, E-08028 Barcelona, Spain

[2] Univ Murcia, Dept Ingn Quim Murcia, Murcia, Spain

[3] Univ Barcelona, Fac Quim, Dept Bioquim & Biol Celular, E-08028 Barcelona, Spain

来源：

BIOTECHNOLOGY LETTERS | 1999年 / 21卷 / 12期

关键词：

biotransformation; oleic acid Pseudomonas sp; 42A2; 10-hydroxy-8E-octadecenoic acid;

D O I：

10.1023/A:1005684704382

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Pseudomonas sp. 42A2 when incubated for 36 h with oleic acid (20 g l(-1)) in a stirred bioreactor, accumulated 10-hydroxy-8E-octadecenoic acid. Production in a 2 l bioreactor with 1.4 l of working volume, was increased from 0.65 g l(-1) to 7.4 g l(-1) with K(L)a values ranging between 15 and 200 h(-1). A linear relationship was found between volumetric productivity and oxygen transfer rates and an exponential relation between the specific rate of product formation and specific growth rate.

引用

页码：1031 / 1035

页数：5

共 9 条

[1]

Blee E, 1995, INFORM, V6, P852

[2] 7,10-DIHYDROXY-8(E)-OCTADECENOIC ACID PRODUCED BY PSEUDOMONAS-42A2 - EVALUATION OF DIFFERENT CULTURAL PARAMETERS OF THE FERMENTATION [J].