Transcription: Adjusting to adversity by regulating RNA polymerase

被引:23
作者
Geiduschek, E. Peter
Kassavetis, George A.
机构
[1] Univ Calif San Diego, Div Biol Sci, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Ctr Genet Mol, La Jolla, CA 92093 USA
关键词
D O I
10.1016/j.cub.2006.08.071
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Under growth-limiting conditions, budding yeast shut down transcription of genes of the translation apparatus. Recent studies have shown that this response is signaled, in part, by multiple pathways that converge on Maf1, leading to a change of this protein's phosphorylation state and its relocation to the nucleus, where it represses RNA polymerase III.
引用
收藏
页码:R849 / R851
页数:3
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