Continuous microflow synthesis of butyl cinnamate by a Mizoroki-Heck reaction using a low-viscosity ionic liquid as the recycling reaction medium

被引：104

作者：

Liu, SF ^{[1
]}

Fukuyama, T ^{[1
]}

Sato, M ^{[1
]}

Ryu, I ^{[1
]}

机构：

[1] Osaka Prefecture Univ, Fac Arts & Sci, Dept Chem, Sakai, Osaka 5998531, Japan

来源：

ORGANIC PROCESS RESEARCH & DEVELOPMENT | 2004年 / 8卷 / 03期

关键词：

D O I：

10.1021/op034200h

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A continuous microflow system was developed with efficient catalyst recycling for a Mizoroki-Heck reaction of iodobenzene with butyl acrylate, using a low-viscosity ionic liquid ([bmim]-NTf2) as the reaction medium. Using a CPC CYTOS Lab System as the microreaction apparatus, in combination with an originally developed microextraction/catalyst recycling system, the reaction medium, which contained Pd catalyst could be continuously recycled to provide a total of 115.3 g (80%, 10 g/h) of the desired product.

引用

页码：477 / 481

页数：5

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