Synthesis of cardamom peroxide analogues by radical cyclization of hydroperoxyalkenes

被引：13

作者：

Cointeaux, L ^{[1
]}

Berrien, JF ^{[1
]}

Mayrargue, J ^{[1
]}

机构：

[1] Fac Pharm Chatenay Malabry, UPRES A 8076, BioCIS, F-92296 Chatenay Malabry, France

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 35期

关键词：

D O I：

10.1016/S0040-4039(02)01122-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three pinenic hydroperoxides were synthesized according to the Dussault method. Two of them could cyclize under radical conditions to give the exo-trig isomer as a single regioisomer. Only five- and six-member ring peroxides were obtained, whereas none of the possible seven-member ones was observed. This strategy could be employed in the total synthesis of cardamom peroxide. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：6275 / 6277

页数：3

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