Concise total synthesis of (±)-aloperine and 6-epi-aloperine

被引：19

作者：

Passarella, D ^{[1
]}

Angoli, M ^{[1
]}

Giardini, A ^{[1
]}

Lesma, G ^{[1
]}

Silvani, A ^{[1
]}

Danieli, B ^{[1
]}

机构：

[1] Univ Milan, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 17期

关键词：

D O I：

10.1021/ol0263144

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Total synthesis of aloperine and 6-epi-aloperine is reported. The crucial steps of the synthetic strategy are an aza-annulation reaction and an intermolecular Diels-Alder reaction. The synthetic plan proceeds from commercially available piperidine-2-ethanol.

引用

页码：2925 / 2928

页数：4

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