High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline

被引：60

作者：

Beteva, A.

Cipriani, F.

Cusack, S.

Delageniere, S.

Gabadinho, J.

Gordon, E. J.

Guijarro, M.

Hall, D. R.

Larsen, S.

Launer, L.

Lavault, C. B.

Leonard, G. A.

Mairs, T.

McCarthy, A.

McCarthy, J.

Meyer, J.

Mitchell, E.

Monaco, S.

Nurizzo, D.

Pernot, P.

Pieritz, R.

Ravelli, R. G. B.

Rey, V.

Shepard, W.

Spruce, D.

Stuart, D. I.

Svensson, O.

Theveneau, P.

Thibault, X.

Turkenburg, J.

Walsh, M.

McSweeney, S. M.

机构：

[1] European Synchrotron Radiat Facil, F-38043 Grenoble, France

[2] European Mol Biol Lab, F-38042 Grenoble, France

[3] MRC, F-38042 Grenoble 9, France

[4] Oxford Prot Prod Facil, Oxford OX3 7BN, England

[5] Well Trust Ctr Human Genet, Div Struct Biol, Oxford OX3 7BN, England

[6] Univ York, Dept Chem, York Struct Biol Lab, York YO10 5DD, N Yorkshire, England

来源：

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY | 2006年 / 62卷

基金：

英国医学研究理事会;

关键词：

D O I：

10.1107/S0907444906032859

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An automatic data- collection system has been implemented and installed on seven insertion- device beamlines and a bending- magnet beamline at the ESRF ( European Synchrotron Radiation Facility) as part of the SPINE ( Structural Proteomics In Europe) development of an automated structure- determination pipeline. The system allows remote interaction with beamline- control systems and automatic sample mounting, alignment, characterization, data collection and processing. Reports of all actions taken are available for inspection via database modules and web services.

引用

页码：1162 / 1169

页数：8

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