Successful treatment of refractory disseminated Mycobacterium avium complex infection with the addition of linezolid and mefloquine

被引:40
作者
Nannini, EC
Keating, M
Binstock, P
Samonis, G
Kontoyiannis, DP
机构
[1] Univ Texas, MD Anderson Canc Ctr, Dept Infect Dis, Houston, TX 77030 USA
[2] Univ Texas, MD Anderson Canc Ctr, Dept Leukemia, Houston, TX 77030 USA
[3] John Muir Med Ctr, Infect Dis Specialists Med Grp, Concord, CA USA
关键词
D O I
10.1053/jinf.2002.0970
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Except in patients with AIDS, disseminated MAC infection has been rare. We describe a patient with chronic lymphatic leukemia who developed disseminated cutaneous MAC lesions refractory to conventional antimycobacterial therapy. The lesions responded to the addition of compounds that were recently discovered to have anti-MAC activity (linezolid, mefloquine, moxifloxacin) as well as GM-CSF. (C) 2002 The British Infection Society.
引用
收藏
页码:201 / 203
页数:3
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