Microwave enhanced reduction of nitro and azido arenes to N-arylformamides employing Zn-HCOONH4:: synthesis of 4(3H)-quinazolinones and pyrrolo[2,1-c][1,4]benzodiazepines

被引：71

作者：

Kamal, A ^{[1
]}

Reddy, KS ^{[1
]}

Prasad, BR ^{[1
]}

Babu, AH ^{[1
]}

Ramana, AV ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 34期

关键词：

zinc; ammonium formate; azides; nitroarenes; N-arylformamides; microwave; 4(3H)-quinazolinones; pyrrolo[2,1-c][1,4]benzodiazepines;

D O I：

10.1016/j.tetlet.2004.06.112

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Microwave mediated reduction of nitro and azido arenes to N-arylformamides using Zn-HCOONH4 is described. In the absence of microwave conditions, this methodology affords amines. This protocol has been extended to the synthesis of pyrrolo[2,1-c][1,4]benzodiazepines and 4(3H)-quinazolinones. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：6517 / 6521

页数：5

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