Microarrays by structured substrate swelling

被引：17

作者：

Bonaccurso, E

Butt, HJ

Graf, K

机构：

[1] Max Planck Inst Polymer Res, D-55128 Mainz, Germany

[2] Univ Siegen, D-57068 Siegen, Germany

来源：

EUROPEAN POLYMER JOURNAL | 2004年 / 40卷 / 05期

关键词：

microstructuring; swelling; microarray;

D O I：

10.1016/j.eurpolymj.2004.01.022

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A technique is presented for manufacturing surface microstructures on polymer substrates. It is based on the uptake of solvent vapors by a prestructured polymer, selective swelling, and the flow of the softened polymer. Prestructuring is done by evaporating material, UV illumination, or ion bombardment through a mask. As an application we describe the fabrication of two-dimensional ordered arrays of microvessels which can be of different shape, size, and material. The bottom of the microvessels can be functionalized by several means and it can be transparent to allow for optical analysis. Applications of the microvessel array are seen in combinatorial chemistry, as microreactors, and as confined spaces for controlling crystal growth. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：975 / 980

页数：6

共 29 条

[1] Control of crystal nucleation by patterned self-assembled monolayers [J].