Regio- and diastereoselective alkylation of 2-substituted 2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones

被引：30

作者：

MartinSantamaria, S ^{[1
]}

Buenadicha, FL ^{[1
]}

Espada, M ^{[1
]}

Sollhuber, M ^{[1
]}

Avendano, C ^{[1
]}

机构：

[1] UNIV COMPLUTENSE MADRID,FAC FARM,DEPT QUIM ORGAN & FARMACEUT,E-28040 MADRID,SPAIN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1997年 / 62卷 / 18期

关键词：

D O I：

10.1021/jo970037a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

页码：6424 / 6428

页数：5

共 35 条

[1] DArrigo MC, 1995, J CHEM RES-S, P430
[2] THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE
ENDICOTT, JA
LING, V
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1989, 58 : 137 - 171
[3] FORD JM, 1990, PHARMACOL REV, V42, P155
[4] CIRCUMVENTION OF CONFLUENCE-DEPENDENT RESISTANCE IN A HUMAN MULTI-DRUG-RESISTANT COLON-CANCER CELL-LINE
GARRIDO, C
CHAUFFERT, B
PINARD, D
TIBAUT, F
GENNE, P
ASSEM, M
DIMANCHEBOITREL, MT
[J]. INTERNATIONAL JOURNAL OF CANCER, 1995, 61 (06) : 873 - 879
[5] GOTTESMAN MM, 1988, J BIOL CHEM, V263, P12163
[6] BIOCHEMISTRY OF MULTIDRUG-RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER
GOTTESMAN, MM
PASTAN, I
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1993, 62 : 385 - 427
[7] 5-N-ACETYLARDEEMIN, A NOVEL HETEROCYCLIC COMPOUND WHICH REVERSES MULTIPLE-DRUG RESISTANCE IN TUMOR-CELLS .2. ISOLATION AND ELUCIDATION OF THE STRUCTURE OF 5-N-ACETYLARDEEMIN AND 2 CONGENERS
HOCHLOWSKI, JE
MULLALLY, MM
SPANTON, SG
WHITTERN, DN
HILL, P
MCALPINE, JB
[J]. JOURNAL OF ANTIBIOTICS, 1993, 46 (03) : 380 - 386
[8] 5-N-ACETYLARDEEMIN, A NOVEL HETEROCYCLIC COMPOUND WHICH REVERSES MULTIPLE-DRUG RESISTANCE IN TUMOR-CELLS .1. TAXONOMY AND FERMENTATION OF THE PRODUCING ORGANISM AND BIOLOGICAL-ACTIVITY
KARWOWSKI, JP
JACKSON, M
RASMUSSEN, RR
HUMPHREY, PE
PODDIG, JB
KOHL, WL
SCHERR, MH
KADAM, S
MCALPINE, JB
[J]. JOURNAL OF ANTIBIOTICS, 1993, 46 (03) : 374 - 379
[9] KELLEN JA, 1993, ANTICANCER RES, V13, P959
[10] AN IMPROVED SYNTHESIS OF (R)-2-METHYLPIPERAZINE AND (S)-2-METHYLPIPERAZINE
KIELY, JS
PRIEBE, SR
[J]. ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 1990, 22 (06) : 761 - 764

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