The GABA(B) receptor antagonist CGP 36 742 and the nootropic oxiracetam facilitate the formation of long-term memory

被引：42

作者：

Mondadori, C ^{[1
]}

Mobius, HJ ^{[1
]}

Borkowski, J ^{[1
]}

机构：

[1] CIBA GEIGY AG,PHARMACEUT RES DEPT,CH-4002 BASEL,SWITZERLAND

来源：

BEHAVIOURAL BRAIN RESEARCH | 1996年 / 77卷 / 1-2期

关键词：

CGP; 36; 742; GABA(B); oxiracetam; memory; mouse;

D O I：

10.1016/0166-4328(95)00222-7

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

The memory-enhancing effects of a single treatment with the GABA, antagonist CGP 36 742 (10 mg/kg) or the nootropic agent oxiracetam (100 mg/kg) given immediately after a learning experience ('post-trial') remain detectable for at least 4 months thereafter. This indicates that in all probability these substances facilitate the formation of the long-term memory trace.

引用

页码：223 / 225

页数：3

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