Substituent effect of 3,3,3-trifluoropropyl group on organic silanols. Palladium-mediated Mizoroki-Heck type and cross-coupling reactions

被引：33

作者：

Hirabayashi, K ^{[1
]}

Kondo, T ^{[1
]}

Toriyama, F ^{[1
]}

Nishihara, Y ^{[1
]}

Mori, A ^{[1
]}

机构：

[1] Tokyo Inst Technol, Resources Utilizat Res Lab, Yokohama, Kanagawa 2268503, Japan

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 2000年 / 73卷 / 03期

关键词：

D O I：

10.1246/bcsj.73.749

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Mizoroki-Heck type reaction of methyl(phenyl)(3,3,3-trifluoropropyl)silanol (1a) with ethyl acrylate in the presence of Pd(OAc)(2) (10 mol%) and Cu(OAc)(2)/LiOAc gave ethyl cinnamate in 70% yield. The palladium-catalyzed cross-coupling of la with 4-iodomethoxybenzene in the presence of Ag2O also afforded 4-methoxybiphenyl in 51% yield.

引用

页码：749 / 750

页数：2

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