Tumor Gompertzian growth by cellular energetic balance

被引:16
作者
Castorina, Paolo
Zappalà, Dario
机构
[1] Ist Nazl Fis Nucl, Sez Catania, I-95123 Catania, Italy
[2] Univ Catania, Dept Phys, I-95123 Catania, Italy
关键词
tumor growth; Gompertz law; multicellular tumor; spheroids;
D O I
10.1016/j.physa.2005.09.063
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
A macroscopic approach to the tumor Gompertzian growth is proposed and successfully applied to the multicellular tumor spheroid data. It is based on the energetic balance among the different cell activities, related to the growth inhibitor factors. The main results can also be described by methods of statistical mechanics. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:473 / 480
页数:8
相关论文
共 19 条
[1]  
Bajzer Z, 1999, GROWTH DEVELOP AGING, V63, P3
[2]  
BAJZER Z, 1997, SURVEY MODEL TUMOR I
[3]  
BELLOMO N, 2004, MATH TOPICS MODELLIN
[4]   Super-rough dynamics on tumor growth [J].
Bru, A ;
Pastor, JM ;
Fernaud, I ;
Bru, I ;
Melle, S ;
Berenguer, C .
PHYSICAL REVIEW LETTERS, 1998, 81 (18) :4008-4011
[5]  
CASTORINA P, UNPUB
[6]   Thermodynamics and evolution [J].
Demetrius, L .
JOURNAL OF THEORETICAL BIOLOGY, 2000, 206 (01) :1-16
[7]   INVASIVE GROWTH OF MALIGNANT-TUMORS AS A PURELY MECHANICAL PROCESS [J].
EAVES, G .
JOURNAL OF PATHOLOGY, 1973, 109 (03) :233-&
[8]  
FREYER JP, 1986, CANCER RES, V46, P3504
[9]  
Gompertz B, 1825, PHILOS T ROY SOC LON, V115, P513, DOI DOI 10.1098/RSTL.1825.0026
[10]   Does tumor growth follow a "universal law"? [J].
Guiot, C ;
Degiorgis, PG ;
Delsanto, PP ;
Gabriele, P ;
Deisboeck, TS .
JOURNAL OF THEORETICAL BIOLOGY, 2003, 225 (02) :147-151