Biomedical applications of terahertz technology

被引:700
作者
Pickwell, E. [1 ]
Wallace, V. P. [1 ]
机构
[1] TeraView Ltd, Cambridge CB4 0WS, England
关键词
D O I
10.1088/0022-3727/39/17/R01
中图分类号
O59 [应用物理学];
学科分类号
摘要
We review the development of terahertz (THz) technology and describe a typical system used in biomedical applications. By considering where the THz regime lies in the electromagnetic spectrum, we see that THz radiation predominantly excites vibrational modes that are present in water. Thus, water absorption dominates spectroscopy and imaging of soft tissues. However, there are advantages of THz methods that make it attractive for pharmaceutical and clinical applications. In this review, we consider applications ranging from THz spectroscopy of crystalline drugs to THz imaging of skin cancer.
引用
收藏
页码:R301 / R310
页数:10
相关论文
共 69 条
[1]   A combined instantaneous normal mode and time correlation function description of the infrared vibrational spectrum of ambient water [J].
Ahlborn, H ;
Ji, XD ;
Space, B ;
Moore, PB .
JOURNAL OF CHEMICAL PHYSICS, 1999, 111 (23) :10622-10632
[2]   Applications of Terahertz (THz) technology to medical imaging [J].
Arnone, DD ;
Ciesla, CM ;
Corchia, A ;
Egusa, S ;
Pepper, M ;
Chamberlain, JM ;
Bezant, C ;
Linfield, EH ;
Clothier, R ;
Khammo, N .
TERAHERTZ SPECTROSCOPY AND APPLICATIONS 11, 1999, 3828 :209-219
[3]   PICOSECOND OPTOELECTRONIC SWITCHING AND GATING IN SILICON [J].
AUSTON, DH .
APPLIED PHYSICS LETTERS, 1975, 26 (03) :101-103
[4]   Heterodyne mixing of two far-infrared quantum cascade lasers by use of a point-contact Schottky diode [J].
Barbieri, S ;
Alton, J ;
Beere, HE ;
Linfield, EH ;
Ritchie, DA ;
Withington, S ;
Scalari, G ;
Ajili, L ;
Faist, J .
OPTICS LETTERS, 2004, 29 (14) :1632-1634
[5]   2.9 THz quantum cascade lasers operating up to 70 K in continuous wave [J].
Barbieri, S ;
Alton, J ;
Beere, HE ;
Fowler, J ;
Linfield, EH ;
Ritchie, DA .
APPLIED PHYSICS LETTERS, 2004, 85 (10) :1674-1676
[6]  
BARBIERI S, 2005, COMMUNICATION
[7]  
Beard MC, 2002, ACS SYM SER, V820, P44
[8]   Subpicosecond carrier dynamics in low-temperature grown GaAs as measured by time-resolved terahertz spectroscopy [J].
Beard, MC ;
Turner, GM ;
Schmuttenmaer, CA .
JOURNAL OF APPLIED PHYSICS, 2001, 90 (12) :5915-5923
[9]   Terahertz spectroscopy [J].
Beard, MC ;
Turner, GM ;
Schmuttenmaer, CA .
JOURNAL OF PHYSICAL CHEMISTRY B, 2002, 106 (29) :7146-7159
[10]   PHOTOMIXING UP TO 3.8-THZ IN LOW-TEMPERATURE-GROWN GAAS [J].
BROWN, ER ;
MCINTOSH, KA ;
NICHOLS, KB ;
DENNIS, CL .
APPLIED PHYSICS LETTERS, 1995, 66 (03) :285-287