An efficient oxidation of 2-aryl-1,2,3,4-tetrahydro-4-quinolones employing ferric chloride hexahydrate-methanol: synthesis of naturally occurring 4-alkoxy-2-arylquinolines

被引：25

作者：

Kumar, KH ^{[1
]}

Muralidharan, D ^{[1
]}

Perumal, PT ^{[1
]}

机构：

[1] Cent Leather Res Inst, Div Organ Chem, Madras 600020, Tamil Nadu, India

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 42期

关键词：

oxidation; FeCl3-6H(2)O-methanol; 2-aryl-1,1,2,3,4-tetrahydroquinolones and benzofurodihydropyridinones;

D O I：

10.1016/j.tetlet.2004.08.144

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple, inexpensive and efficient oxidation of 2-aryl-1,2,3,4-tetrahydro-4-quinolones has been carried out by employing FeCl3-6H(2)O-methanol under mild conditions. This method has been investigated for the synthesis of an endothelin receptor antagonist, benzofuro[3,2-b]pyridine core structure. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：7903 / 7906

页数：4

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