Bupropion sustained release for the treatment of hypoactive sexual desire disorder in premenopausal women

被引:116
作者
Segraves, RT
Clayton, A
Croft, H
Wolf, A
Warnock, J
机构
[1] Case Western Reserve Univ, Dept Psychiat, Cleveland, OH 44109 USA
[2] MetroHlth Med Syst, Cleveland, OH USA
[3] Univ Virginia, Dept Psychiat, Charlottesville, VA USA
[4] Univ Oklahoma, Dept Psychiat, Oklahoma City, OK USA
关键词
D O I
10.1097/01.jcp.0000125686.20338.c1
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Premenopausal women meeting operational criteria for idiopathic, acquired, global hypoactive sexual desire disorder were studied in a randomized, double-blind, placebo-controlled, multiple-site escalating dose 112-day trial of bupropion sustained release. Outcome was measured by investigator-rating and self-administered questionnaires. All measures indicated greater sexual responsiveness in women receiving bupropion. The Changes in Sexual Functioning Questionnaire indicated that bupropion had significant effects on increasing measures of sexual arousal, orgasm completion, and sexual satisfaction.
引用
收藏
页码:339 / 342
页数:4
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