Defensins: antimicrobial peptides of vertebrates

被引:147
作者
Ganz, T [1 ]
机构
[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Los Angeles, CA 90095 USA
关键词
antimicrobial peptides; innate immunity; defensins; cysteine;
D O I
10.1016/j.crvi.2003.12.007
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
This review, based on my presentation at the French Academy of Sciences on May 19, 2003, describes recent progress in the study of antimicrobial peptides, mediators of innate immunity in plants and animals. The main focus is on vertebrate defensins, a family of cysteine-rich antimicrobial peptides abundantly represented in human cells and tissues. (C) 2004 Academie des sciences. Published by Elsevier SAS. All rights reserved.
引用
收藏
页码:539 / 549
页数:11
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