SEBINI: Software Environment for BIological Network Inference

被引:17
作者
Taylor, Ronald C. [1 ]
Shah, Anuj
Treatman, Charles
Blevins, Meridith
机构
[1] Pacific NW Natl Lab, Computat Biol & Bioinformat Grp, Richland, WA 99352 USA
[2] Oberlin Coll, Oberlin, OH 44074 USA
[3] Case Western Reserve Univ, Cleveland, OH 44106 USA
关键词
D O I
10.1093/bioinformatics/btl444
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The Software Environment for BIological Network Inference (SEBINI) has been created to provide an interactive environment for the deployment and evaluation of algorithms used to reconstruct the structure of biological regulatory and interaction networks. SEBINI can be used to compare and train network inference methods on artificial networks and simulated gene expression perturbation data. It also allows the analysis within the same framework of experimental high-throughput expression data using the suite of (trained) inference methods; hence SEBINI should be useful to software developers wishing to evaluate, compare, refine or combine inference techniques, and to bioinformaticians analyzing experimental data. SEBINI provides a platform that aids in more accurate reconstruction of biological networks, with less effort, in less time.
引用
收藏
页码:2706 / 2708
页数:3
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