Psychophysiology of post-traumatic stress disorder

被引:134
作者
Orr, SP [1 ]
Metzger, LJ
Pitman, RK
机构
[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Psychiat, Charlestown, MA 02129 USA
[2] Dept Vet Affairs Med Ctr, Res Serv, Manchester, NH USA
关键词
D O I
10.1016/S0193-953X(01)00007-7
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Clinical observations supporting an association between exposure to life-threatening events and altered physiologic arousal, especially overactivity or over-reactivity of the sympathetic nervous system, has made post-traumatic stress disorder (PTSD) an obvious target for psychophysiologic research. A variety of physiologic and cognitive symptoms and features of PTSD have lent themselves especially well to this type of investigation. These have included heightened responsiveness to reminders of a traumatic event, exaggerated startle, elevated autonomic arousal, hypervigilance, and concentration difficulties. Psychophysiologic and electrophysiologic findings addressing these and related issues in PTSD are reviewed.
引用
收藏
页码:271 / +
页数:25
相关论文
共 114 条
[71]   Differences between males and females in rates of serotonin synthesis in human brain [J].
Nishizawa, S ;
Benkelfat, C ;
Young, SN ;
Leyton, M ;
Mzengeza, S ;
DeMontigny, C ;
Blier, P ;
Diksic, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (10) :5308-5313
[72]  
OPPENHEIMER BS, 1918, BMJ-BRIT MED J, V13, P29
[73]  
ORNITZ EM, 1989, AM J PSYCHIAT, V146, P866
[74]   Heart rate and blood pressure resting levels and responses to generic stressors in Vietnam veterans with posttraumatic stress disorder [J].
Orr, SP ;
Meyerhoff, JL ;
Edwards, JV ;
Pitman, RK .
JOURNAL OF TRAUMATIC STRESS, 1998, 11 (01) :155-164
[75]   PSYCHOPHYSIOLOGICAL ASSESSMENT OF POSTTRAUMATIC-STRESS-DISORDER IMAGERY IN WORLD-WAR-II AND KOREAN COMBAT VETERANS [J].
ORR, SP ;
PITMAN, RK ;
LASKO, NB ;
HERZ, LR .
JOURNAL OF ABNORMAL PSYCHOLOGY, 1993, 102 (01) :152-159
[76]   Psychophysiologic assessment of women with posttraumatic stress disorder resulting from childhood sexual abuse [J].
Orr, SP ;
Lasko, NB ;
Metzger, LJ ;
Berry, NJ ;
Ahern, CE ;
Pitman, RK .
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY, 1998, 66 (06) :906-913
[77]   Physiologic responses to non-startling tones in Vietnam veterans with post-traumatic stress disorder [J].
Orr, SP ;
Lasko, NB ;
Metzger, LJ ;
Pitman, RK .
PSYCHIATRY RESEARCH, 1997, 73 (1-2) :103-107
[78]   Psychophysiologic assessment of PTSD in adult females sexually abused during childhood [J].
Orr, SP ;
Lasko, NB ;
Metzger, LJ ;
Berry, NJ ;
Ahern, CE ;
Pitman, RK .
PSYCHOBIOLOGY OF POSTTRAUMATIC STRESS DISORDER, 1997, 821 :491-493
[79]   De novo conditioning in trauma-exposed individuals with and without posttraumatic stress disorder [J].
Orr, SP ;
Metzger, LJ ;
Lasko, NB ;
Macklin, ML ;
Peri, T ;
Pitman, RK .
JOURNAL OF ABNORMAL PSYCHOLOGY, 2000, 109 (02) :290-298
[80]   Physiologic responses to loud tones in Israeli veterans of the 1973 Yom Kippur war [J].
Orr, SP ;
Solomon, Z ;
Peri, T ;
Pitman, RK ;
Shalev, AY .
BIOLOGICAL PSYCHIATRY, 1997, 41 (03) :319-326