Antibacterial Activity of Thai Medicinal Plants against Methicillin-resistant Staphylococcus aureus

被引：78

作者：

Chomnawang, Mullika Traidej ^{[1
]}

Surassmo, Suvimol ^{[1
]}

Wongsariya, Karn ^{[1
]}

Bunyapraphatsara, Nuntavan ^{[2
]}

机构：

[1] Mahidol Univ, Fac Pharm, Dept Microbiol, Bangkok 10400, Thailand

[2] Mahidol Univ, Fac Pharm, Dept Pharmacognosy, Bangkok 10400, Thailand

来源：

FITOTERAPIA | 2009年 / 80卷 / 02期

关键词：

Methicillin-resistant S. aureus; Medicinal plants; Antibacterial activity; Bioautography; Garcinia mangostana; alpha-mangostin; GARCINIA-MANGOSTANA; ANTIMICROBIAL ACTIVITIES; CHEMICAL-CONSTITUENTS;

D O I：

10.1016/j.fitote.2008.10.007

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Methicillin-resistant Staphylococcus aureus (MRSA) is a major nosocomial pathogen which causes severe morbidity and mortality worldwide. Seventeen Thai medicinal plants were investigated for their activity against MRSA. Garcinia mangostana was identified as the most potent plant, and its activity was traced to the prenylated xanthone, of-mangostin (MIC and MBC values of 1.95 and 3.91 mu g/ml, respectively). (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：102 / 104

页数：3

共 15 条

[1] Active constituents against HIV-1 protease from Garcinia mangostana [J].

Chen, SX ;

Wan, M ;

Loh, BN .

PLANTA MEDICA, 1996, 62 (04) :381-382

[2] Antimicrobial effects of Thai medicinal plants against acne-inducing bacteria [J].

Chomnawang, MT ;

Surassmo, S ;

Nukoolkarn, VS ;

Gritsanapan, W .

JOURNAL OF ETHNOPHARMACOLOGY, 2005, 101 (1-3) :330-333

[3] Effect of Garcinia mangostana on inflammation caused by Propionibacterium acnes [J].

Chomnawang, Mullika Traidej ;

Surassmo, Suvimol ;

Nukoolkarn, Veena S. ;

Gritsanapan, Wandee .

FITOTERAPIA, 2007, 78 (06) :401-408

[4]

GOPALAKRISHNAN C, 1980, INDIAN J EXP BIOL, V18, P843

[5] Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives [J].

Gopalakrishnan, G ;

Banumathi, B ;

Suresh, G .

JOURNAL OF NATURAL PRODUCTS, 1997, 60 (05) :519-524

[6] Methicillin resistant Staphylococcus aureus (MRSA) in the intensive care unit [J].

Haddadin, AS ;

Fappiano, SA ;

Lipsett, PA .

POSTGRADUATE MEDICAL JOURNAL, 2002, 78 (921) :385-392

[7]

HERWALDT LA, 1999, AM J MED, V106, P11, DOI DOI 10.1016/S0002-9343(98)00350-7

[8] Antibacterial activity of xanthones from guttiferaeous plants against methicillin-resistant Staphylococcus aureus [J].

Iinuma, M ;

Tosa, H ;

Tanaka, T ;

Asai, F ;

Kobayashi, Y ;

Shimano, R ;

Miyauchi, KI .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1996, 48 (08) :861-865

[9] Medical progress -: Staphylococcus aureus infections [J].

Lowy, FD .

NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (08) :520-532

[10]

MAHABUSARAKAM W, 1986, J SCI SOC THAILAND, V12, P239

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