A role for antigen in the maintenance of immunological memory

被引：96

作者：

Gray, D ^{[1
]}

机构：

[1] Univ Edinburgh, Ashworth Labs, Inst Cell Anim & Populat Biol, Edinburgh EH9 3JT, Midlothian, Scotland

来源：

NATURE REVIEWS IMMUNOLOGY | 2002年 / 2卷 / 01期

基金：

英国惠康基金; 英国医学研究理事会;

关键词：

D O I：

10.1038/nri706

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The immune system has a memory that it exhibits in the enhanced and augmented responses the second time it meets an antigen. The memory is the result of a number of changes to the system brought about during the primary response. The most important of these changes is the formation of an expanded pool of antigen-specific memory cells. One of the enduring questions in immunology is how these memory cells are maintained for such long periods.

引用

页码：60 / 65

页数：6

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