Enantioselective diethylzinc addition to aldehydes catalyzed by Ti(IV) complex of unsymmetrical chiral bis(sulfonamide) ligands of trans-cyclohexane 1,2-diamine

被引：29

作者：

Bisai, Alakesh ^{[1
]}

Singh, Pradeep K. ^{[1
]}

Singh, Vinod K. ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, India

来源：

TETRAHEDRON | 2007年 / 63卷 / 03期

关键词：

D O I：

10.1016/j.tet.2006.11.022

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Titanium(IV) complexes of bidentate trans-cyclohexane 1,2-diamine-based unsymmetrical chiral bis(sulfonamide) ligands were evaluated as catalysts for the asymmetric addition of diethylzinc to aldebydes. The reaction provided secondary alcohols in quantitative yields and very good enantioselectivity (up to 96% ee). (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：598 / 601

页数：4

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