Highly enantioselective addition of Me2Zn to aldehydes catalyzed by ClCr(Salen)

被引：56

作者：

Cozzi, PG ^{[1
]}

Kotrusz, P ^{[1
]}

机构：

[1] Univ Bologna, Dipartimento Chim, I-40126 Bologna, Italy

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 15期

关键词：

D O I：

10.1021/ja057969d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

High enantiomeric excesses are obtained in the addition of Me2Zn catalyzed by commercially available ClCr(Salen). Broad scope, simple procedure, room temperature, low catalyst loading are the characteristics of this new enantioselective process, which uses the rather unreactive Me2Zn. Enantiomeric excesses in the range of 71-99% are obtained with all the aldehydes tested. Copyright © 2006 American Chemical Society.

引用

页码：4940 / 4941

页数：2

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