Tandem organochromium-coupling and epoxide ring opening:: a direct approach for the synthesis of cyclic ethers

被引：10

作者：

González, IC ^{[1
]}

Forsyth, CJ ^{[1
]}

机构：

[1] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 20期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(00)00526-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A two-step protocol for the convergent formation of cyclic ethers has been demonstrated. This involves the chemoselective 1,2-addition of vinylchromium species to a 4,5-epoxy aldehyde to generate phi,delta-epoxy alcohols followed by acid-induced transetherification to generate substituted tetrahydrofuran and pyran products. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3805 / 3807

页数：3

共 8 条

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