Ni(II)/Cr(II)-mediated coupling reaction: Beneficial effects of 4-tert-butylpyridine as an additive and development of new and improved workup procedures

被引：49

作者：

Stamos, DP ^{[1
]}

Sheng, XC ^{[1
]}

Chen, SS ^{[1
]}

Kishi, Y ^{[1
]}

机构：

[1] HARVARD UNIV,DEPT CHEM & BIOL CHEM,CAMBRIDGE,MA 02138

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 36期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(97)01462-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-tert-Butylpyridine has been shown to be a beneficial additive in the Ni(II)/Cr(II)-mediated coupling reaction. This addictive allows for homogeneous reactions, improves reproducibility, and inhibits homo-coupling of vinyl iodides or triflates. Improved workup procedures using chromium ion chelators (ethylenediamine or sodium or potassium serinate) allow for a better mass recovery. (C) 1997 Elsevier Science Ltd.

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收藏

页码：6355 / 6358

页数：4

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