Diterpenoids from Isodon adenantha

被引：30

作者：

Jiang, B

Yang, H

Li, ML

Hou, AJ

Han, QB

Wang, SJ

Li, SH

Sun, HD ^{[1
]}

机构：

[1] Acad Sinica, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China

[2] Kunming Med Coll, Yunnan Lab Pharmacol Nat Prod, Kunming 650031, Peoples R China

[3] Dali Med Coll, Dept Pharmacol, Dalian 671000, Yunnan, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 08期

关键词：

D O I：

10.1021/np020084k

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Eleven new diterpenoids, adenanthins B-L (1-11), together with five known analogues, calcicolin B (12), adenanthin (13), weisiensin A (14), nervosanin (15), and forrestin C (16), were isolated from the aerial parts of Isodon adenantha The structures of 1-11 were elucidated on the basis of spectral methods, as well as the X ray crystallographic analysis of 11 Compounds 2, 5, and 14 showed significant inhibitory activities against K562 cells, with IC50 values less than 4 mug/mL, respectively.

引用

页码：1111 / 1116

页数：6

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