Unexpected formation of 3-substituted 1,2,3,4-tetrahydroisoquinolines during tosylation of N,N-dibenzylaminols

被引：18

作者：

Chandrasekhar, S ^{[1
]}

Mohanty, PK ^{[1
]}

Harikishan, K ^{[1
]}

Sasmal, PK ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 06期

关键词：

D O I：

10.1021/ol9901220

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] An efficient new entry toward the construction of 3 substituted 1,2,3,4-tetrahydroisoquinolines from N,N-dibenzyl-alpha-aminols is reported via intramolecular Friedel-Crafts cyclization of in situ generated tosylate intermediate.

引用

页码：877 / 878

页数：2

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