Diastereoselective reduction of acyclic hydroxyketones and diketones with an indium hydride reagent

被引：31

作者：

Yamada, M ^{[1
]}

Horie, T ^{[1
]}

Kawai, M ^{[1
]}

Yamamura, H ^{[1
]}

Araki, S ^{[1
]}

机构：

[1] NAGOYA INST TECHNOL,DEPT APPL CHEM,SHOWA KU,NAGOYA,AICHI 466,JAPAN

来源：

TETRAHEDRON | 1997年 / 53卷 / 46期

关键词：

D O I：

10.1016/S0040-4020(97)10024-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Hydroxyketones and diketones have been reduced with lithium indium hydride to give meso-diols selectively. alpha-Hydroxyketones and alpha-diketones are reduced to meso-1,2-diols with high diastereoselectivities, whereas the selectivities of beta-hydroxyketones and beta-diketones are less satisfactory. (C) 1997 Elsevier Science Ltd.

引用

页码：15685 / 15690

页数：6

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