Insights into lipid raft structure and formation from experiments in model membranes

被引：222

作者：

London, E ^{[1
]}

机构：

[1] SUNY Stony Brook, Dept Chem, Dept Biochem & Cell Biol, Stony Brook, NY 11794 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2002年 / 12卷 / 04期

关键词：

D O I：

10.1016/S0959-440X(02)00351-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Rafts are sphingolipid/cholesterol-rich lipid domains believed to exist within certain eukaryotic cell membranes. Model membrane studies have been key to understanding the basic physical: principles behind raft formation. Recent fluorescence quenching studies have demonstrated that tight packing between sterols and sphingolipids is the driving force for raft formation, and have begun to decipher the rules governing how different molecules interact with rafts.

引用

页码：480 / 486

页数：7

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