Molecular insights into gastrointestinal neuroendocrine tumours: importance and recent advances

被引：27

作者：

Corleto, VD

Delle Fave, G

Jensen, RT

机构：

[1] NIDDK, DB, Digest Dis Branch, NIH, Bethesda, MD 20892 USA

[2] Univ Roma La Sapienza, Div Digest & Liver Dis, I-00185 Rome, Italy

来源：

DIGESTIVE AND LIVER DISEASE | 2002年 / 34卷 / 09期

关键词：

carcinoid; gastrinoma; Multiple Endocrine Neoplasia type-1; pancreatic endocrine turnour;

D O I：

10.1016/S1590-8658(02)80212-2

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A subset of gastrointestinal neuroendocrine tumours [carcinoids and pancreatic endocrine tumours] show aggressive growth. Early identification of this subset is essential for management; however clinical, laboratory and histologic features frequently fail to achieve this. Currently, there is an increased understanding of the molecular pathogenesis/changes in neuroendocrine tumours and this may identify important prognostic factors and possibly, new treatments. Recent findings and progress in this area are briefly reviewed in this article.

引用

页码：668 / 680

页数：13

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