Human Infection with MERS Coronavirus after Exposure to Infected Camels, Saudi Arabia, 2013

被引：249

作者：

Memish, Ziad A. ^{[1
,2
,3
]}

Cotten, Matthew ^{[4
]}

Meyer, Benjamin ^{[5
]}

Watson, Simon J. ^{[4
]}

Alsahafi, Abdullah J. ^{[6
]}

Al Rabeeah, Abdullah A. ^{[2
,3
]}

Corman, Victor Max ^{[5
]}

Sieberg, Andrea ^{[5
]}

Makhdoom, Hatem Q. ^{[7
]}

Assiri, Abdullah ^{[3
]}

Al Masri, Malaki ^{[3
]}

Aldabbagh, Souhaib ^{[5
]}

Bosch, Berend-Jan ^{[8
]}

Beer, Martin ^{[9
]}

Mueller, Marcel A. ^{[5
]}

Kellam, Paul ^{[4
,10
]}

Drosten, Christian ^{[5
]}

机构：

[1] Al Faisal Univ, Riyadh, Saudi Arabia

[2] Global Ctr Mass Gatherings Med, Riyadh, Saudi Arabia

[3] Minist Hlth, Riyadh, Saudi Arabia

[4] Wellcome Trust Sanger Inst, Hinxton, England

[5] Univ Bonn, Med Ctr, Inst Virol, Bonn, Germany

[6] Reg Hlth Directoracte, Jeddah, Saudi Arabia

[7] Jeddah Reg Lab, Jeddah, Saudi Arabia

[8] Univ Utrecht, NL-3508 TC Utrecht, Netherlands

[9] Friedrich Loeffler Inst, Inst Virus Diagnost, Greifswald, Riems, Germany

[10] UCL, London, England

来源：

EMERGING INFECTIOUS DISEASES | 2014年 / 20卷 / 06期

关键词：

RESPIRATORY SYNDROME CORONAVIRUS; DROMEDARY CAMELS; ANTIBODIES; LIVESTOCK;

D O I：

10.3201/eid2006.140402

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We investigated a case of human infection with Middle East respiratory syndrome coronavirus (MERS-CoV) after exposure to infected camels. Analysis of the whole human-derived virus and 15% of the camel-derived virus sequence yielded nucleotide polymorphism signatures suggestive of cross-species transmission. Camels may act as a direct source of human MERS-CoV infection.

引用

页码：1012 / 1015

页数：4

共 15 条

[1] Alagaili AN, 2014, MBIO, V5, DOI [10.1128/mBio.00884-14, 10.1128/mBio.01482-14]
[2] Buchholz U, 2013, EUROSURVEILLANCE, V18, P6
[3] Chu D.K. W., 2014, EMERG INFECT DIS
[4] Corman VM, 2012, EUROSURVEILLANCE, V17, P2
[5] Corman VM, 2012, EUROSURVEILLANCE, V17, P3
[6] Spread, Circulation, and Evolution of the Middle East Respiratory Syndrome Coronavirus
Cotten, Matthew
Watson, Simon J.
Zumla, Alimuddin I.
Makhdoom, Hatem Q.
Palser, Anne L.
Ong, Swee Hoe
Al Rabeeah, Abdullah A.
Alhakeem, Rafat F.
Assiri, Abdullah
Al-Tawfiq, Jaffar A.
Albarrak, Ali
Barry, Mazin
Shibl, Atef
Alrabiah, Fahad A.
Hajjar, Sami
Balkhy, Hanan H.
Flemban, Hesham
Rambaut, Andrew
Kellam, Paul
Memish, Ziad A.
[J]. MBIO, 2014, 5 (01):
[7] Full-Genome Deep Sequencing and Phylogenetic Analysis of Novel Human Betacoronavirus
Cotten, Matthew
Lam, Tommy T.
Watson, Simon J.
Palser, Anne L.
Petrova, Velislava
Grant, Paul
Pybus, Oliver G.
Rambaut, Andrew
Guan, Yi
Pillay, Deenan
Kellam, Paul
Nastouli, Eleni
[J]. EMERGING INFECTIOUS DISEASES, 2013, 19 (05) : 736 - 742
[8] Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation
Haagmans, Bart L.
Al Dhahiry, Said H. S.
Reusken, Chantal B. E. M.
Raj, V. Stalin
Galiano, Monica
Myers, Richard
Godeke, Gert-Jan
Jonges, Marcel
Farag, Elmoubasher
Diab, Ayman
Ghobashy, Hazem
Alhajri, Farhoud
Al-Thani, Mohamed
Al-Marri, Salih A.
Al Romaihi, Hamad E.
Al Khal, Abdullatif
Bermingham, Alison
Osterhaus, Albert D. M. E.
AlHajri, Mohd M.
Koopmans, Marion P. G.
[J]. LANCET INFECTIOUS DISEASES, 2014, 14 (02) : 140 - 145
[9] Middle East Respiratory Syndrome (MERS) coronavirus seroprevalence in domestic livestock in Saudi Arabia, 2010 to 2013
Hemida, M. G.
Perera, R. A.
Wang, P.
Alhammadi, M. A.
Siu, L. Y.
Li, M.
Poon, L. L.
Saif, L.
Alnaeem, A.
Peiris, M.
[J]. EUROSURVEILLANCE, 2013, 18 (50): : 21 - 27
[10] Antibodies against MERS Coronavirus in Dromedaries, United Arab Emirates, 2003 and 2013
Meyer, Benjamin
Mueller, Marcel A.
Corman, Victor M.
Reusken, Chantal B. E. M.
Ritz, Daniel
Godeke, Gert-Jan
Lattwein, Erik
Kallies, Stephan
Siemens, Artem
van Beek, Janko
Drexler, Jan F.
Muth, Doreen
Bosch, Berend-Jan
Wernery, Ulrich
Koopmans, Marion P. G.
Wernery, Renate
Drosten, Christian
[J]. EMERGING INFECTIOUS DISEASES, 2014, 20 (04) : 552 - 559

← 1 2 →