Monoallelic gene expression in mammals

被引：33

作者：

Zakharova, Irina S. ^{[1
]}

Shevchenko, Alexander I. ^{[1
]}

Zakian, Suren M. ^{[1
]}

机构：

[1] Russian Acad Sci, Inst Cytol & Genet, Siberian Dept, Novosibirsk 630090, Russia

来源：

CHROMOSOMA | 2009年 / 118卷 / 03期

基金：

俄罗斯基础研究基金会;

关键词：

MATERNAL-SPECIFIC METHYLATION; ANTISENSE INTERGENIC TRANSCRIPTION; REPRESSIVE HISTONE METHYLATION; X-INACTIVATION; ASYNCHRONOUS REPLICATION; INTRONIC ENHANCER; NONCODING RNA; PROMOTER DETERMINES; DOSAGE COMPENSATION; V(D)J RECOMBINATION;

D O I：

10.1007/s00412-009-0206-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three systems of monoallelic gene expression in mammals are known, namely, X-chromosome inactivation, imprinting, and allelic exclusion. In all three systems, monoallelic expression is regulated epigenetically and is frequently directed by long non-coding RNAs (ncRNAs). This review briefs all three systems of monoallelic gene expression in mammals focusing on chromatin modifications, spatial chromosome organization in the nucleus, and the functioning of ncRNAs.

引用

页码：279 / 290

页数：12

共 100 条

[1] Regulation of IgH gene assembly:: Role of the intronic enhancer and 5′DQ52 region in targeting DHJH recombination [J].

Afshar, R ;

Pierce, S ;

Bolland, DJ ;

Corcoran, A ;

Oltz, EM .

JOURNAL OF IMMUNOLOGY, 2006, 176 (04) :2439-2447

[2] Differences between homologous alleles of olfactory receptor genes require the Polycomb Group protein Eed [J].

Alexander, Mary Kate ;

Mlynarczyk-Evans, Susanna ;

Royce-Tolland, Morgan ;

Plocik, Alex ;

Kalantry, Sundeep ;

Magnuson, Terry ;

Panning, Barbara .

JOURNAL OF CELL BIOLOGY, 2007, 179 (02) :269-276

[3] Sensing X chromosome pairs before X inactivation via a novel X-pairing region of the Xic [J].

Augui, S. ;

Filion, G. J. ;

Huart, S. ;

Nora, E. ;

Guggiari, M. ;

Maresca, M. ;

Stewart, A. F. ;

Heard, E. .

SCIENCE, 2007, 318 (5856) :1632-1636

[4]

Bacher CP, 2006, NAT CELL BIOL, V8, P293, DOI 10.1038/ncb1365

[5] Competition - a common motif for the imprinting mechanism? [J].

Barlow, DP .

EMBO JOURNAL, 1997, 16 (23) :6899-6905

[6] Nuclear architecture in the light of gene expression and cell differentiation studies [J].

Bartova, Eva ;

Kozubek, Stanislav .

BIOLOGY OF THE CELL, 2006, 98 (06) :323-336

[7] The mechanism and regulation of chromosomal V(D)J recombination [J].

Bassing, CH ;

Swat, W ;

Alt, FW .

CELL, 2002, 109 :S45-S55

[8]

BEECHEY CV, 2008, MOUSE IMPRINTING DAT

[9]

BLANK RD, 1988, GENETICS, V120, P1073

[10] Antisense Intergenic transcription precedes Igh D-to-J recombination and is controlled by the intronic enhancer Eμ [J].

Bolland, Daniel J. ;

Wood, Andrew L. ;

Afshar, Roshi ;

Featherstone, Karen ;

Oltz, Eugene M. ;

Corcoran, Anne E. .

MOLECULAR AND CELLULAR BIOLOGY, 2007, 27 (15) :5523-5533

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