The art and design of genetic screens: Filamentous fungi

被引：57

作者：

Casselton, L

Zolan, M

机构：

[1] Univ Oxford, Dept Plant Sci, Oxford OX1 3RB, England

[2] Indiana Univ, Dept Biol, Bloomington, IN 47405 USA

来源：

NATURE REVIEWS GENETICS | 2002年 / 3卷 / 09期

基金：

美国国家卫生研究院; 英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1038/nrg889

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

In the 1940s, screens for metabolic mutants of the filamentous fungus Neurospora crassa established the fundamental, one-to-one relationship between a gene and a specific protein, and also established fungi as important genetic organisms. Today, a wide range of filamentous species, which represents a billion years of evolutionary divergence, is used for experimental studies. The developmental complexity of these fungi sets them apart from unicellular yeasts, and allows the development of new screens that enable us to address biological questions that are relevant to all eukaryotes.

引用

收藏

页码：683 / 697

页数：15

相关论文

共 116 条

[1] Mitosis in filamentous fungi: How we got where we are [J].

Aist, JR ;

Morris, NR .

FUNGAL GENETICS AND BIOLOGY, 1999, 27 (01) :1-25

[2] 2-WAY SELECTION OF MUTANTS AND REVERTANTS IN RESPECT OF ACETATE UTILIZATION AND RESISTANCE TO FLUORO-ACETATE IN ASPERGILLUS NIDULANS [J].

APIRION, D .

GENETICAL RESEARCH, 1965, 6 (03) :317-&

[3] T-DNA insertion mutagenesis in Arabidopsis: Going back and forth [J].

AzpirozLeehan, R ;

Feldmann, KA .

TRENDS IN GENETICS, 1997, 13 (04) :152-156

[4] Genetics of Ustilago maydis, a fungal pathogen that induces tumors in maize [J].

Banuett, F .

ANNUAL REVIEW OF GENETICS, 1995, 29 :179-208

[5] Use of a linear plasmid containing telomeres as an efficient vector for direct cloning in the filamentous fungus Podospora anserina [J].

Barreau, C ;

Iskandar, M ;

Turcq, B ;

Javerzat, JP .

FUNGAL GENETICS AND BIOLOGY, 1998, 25 (01) :22-30

[6] Genetic control of biochemical reactions in neurospora [J].

Beadle, GW ;

Tatum, EL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1941, 27 :499-506

[7] Understanding circadian rhythmicity in Neurospora crassa:: From behavior to genes and back again [J].

Bell-Pedersen, D .

FUNGAL GENETICS AND BIOLOGY, 2000, 29 (01) :1-18

[8] DATING THE EVOLUTIONARY RADIATIONS OF THE TRUE FUNGI [J].

BERBEE, ML ;

TAYLOR, JW .

CANADIAN JOURNAL OF BOTANY-REVUE CANADIENNE DE BOTANIQUE, 1993, 71 (08) :1114-1127

[9] Genetic interactions among cytoplasmic dynein, dynactin, and nuclear distribution mutants of Neurospora crassa [J].

Bruno, KS ;

Tinsley, JH ;

Minke, PF ;

Plamann, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (10) :4775-4780

[10] Mate recognition in fungi [J].

Casselton, LA .

HEREDITY, 2002, 88 (2) :142-147

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