The interface between obesity and periodontitis with emphasis on oxidative stress and inflammatory response

被引:65
作者
Boesing, F. [2 ]
Patino, J. S. R. [3 ]
da Silva, V. R. G. [2 ]
Moreira, E. A. M. [1 ]
机构
[1] Univ Fed Santa Catarina, Dept Nutr, Ctr Ciencias Saude, Postgrad Programs Nutr & Dent, BR-88040970 Florianopolis, SC, Brazil
[2] Univ Fed Santa Catarina, Postgrad Program Nutr, BR-88040970 Florianopolis, SC, Brazil
[3] Univ Fed Santa Catarina, Postgrad Program Dent, BR-88040970 Florianopolis, SC, Brazil
关键词
Adipose tissue; free radicals; inflammation; periodontitis; NECROSIS-FACTOR-ALPHA; C-REACTIVE PROTEIN; WEIGHT-LOSS; LIPID-PEROXIDATION; INSULIN-RESISTANCE; ANTIOXIDANT STATUS; DIETARY RESTRICTION; ADIPOSE-TISSUE; DENTAL STATUS; WHOLE SALIVA;
D O I
10.1111/j.1467-789X.2008.00555.x
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Obesity is characterized by the abnormal or excessive deposition of fat in the adipose tissue. Its consequences go far beyond adverse metabolic effects on health, causing an increase in oxidative stress that leads not only to endothelial dysfunction but also to negative effects in relation to periodontitis, because of the increase in proinflammatory cytokines. Thus, obesity appears to participate in the multifactorial phenomenon of causality of periodontitis through the increased production of reactive oxygen species. Within this context, this paper aims to highlight, by analysis and description of previous studies, the interface between obesity and periodontitis, with emphasis on oxidative stress and the inflammatory response.
引用
收藏
页码:290 / 297
页数:8
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