Cytokine regulation of tight junctions

被引：564

作者：

Capaldo, Christopher T. ^{[1
]}

Nusrat, Asma ^{[1
]}

机构：

[1] Emory Univ, Dept Pathol & Lab Med, Epithelial Pathobiol Res Unit, Atlanta, GA 30322 USA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | 2009年 / 1788卷 / 04期

关键词：

Tight junction; Cytokine; IFN-gamma; TNF-alpha; Claudin; Interleukin; ZO-1; Paracellular permiability; TUMOR-NECROSIS-FACTOR; EPITHELIAL BARRIER FUNCTION; INFLAMMATORY-BOWEL-DISEASE; PROTEIN-KINASE-C; BLOOD-BRAIN-BARRIER; NF-KAPPA-B; INTERFERON-GAMMA; TNF-ALPHA; INTESTINAL PERMEABILITY; PHOSPHORYLATION SITE;

D O I：

10.1016/j.bbamem.2008.08.027

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Epithelial and endothelial tight junctions act as a rate-limiting barrier between an organism and its environment. Continuing studies have highlighted the regulation of the tight junction barrier by cytokines. Elucidation of this interplay is vital for both the understanding of physiological tight junction regulation and the etiology of pathological conditions. This review will focus on recent advances in our understanding of the molecular mechanisms of tight junctions modulation by cytokines. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：864 / 871

页数：8

共 109 条

[51] TNF-α-induced increase in intestinal epithelial tight junction permeability requires NF-κB activation
Ma, TY
Iwamoto, GK
Hoa, NT
Akotia, V
Pedram, A
Boivin, MA
Said, HM
[J]. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2004, 286 (03): : G367 - G376
[52] EFFECTS OF CYTOCHALASIN-D ON OCCLUDING JUNCTIONS OF INTESTINAL ABSORPTIVE CELLS - FURTHER EVIDENCE THAT THE CYTOSKELETON MAY INFLUENCE PARACELLULAR PERMEABILITY AND JUNCTIONAL CHARGE SELECTIVITY
MADARA, JL
BARENBERG, D
CARLSON, S
[J]. JOURNAL OF CELL BIOLOGY, 1986, 102 (06) : 2125 - 2136
[53] INTERFERON-GAMMA DIRECTLY AFFECTS BARRIER FUNCTION OF CULTURED INTESTINAL EPITHELIAL MONOLAYERS
MADARA, JL
STAFFORD, J
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1989, 83 (02) : 724 - 727
[54] Interleukin 10 prevents cytokine-induced disruption of T84 monolayer barrier integrity and limits chloride secretion
Madsen, KL
Lewis, SA
Tavernini, MM
Hibbard, J
Fedorak, RN
[J]. GASTROENTEROLOGY, 1997, 113 (01) : 151 - 159
[55] Tumor necrosis factor-α increases sodium and chloride conductance across the tight junction of CACO-2 BBE, a human intestinal epithelial cell line
Marano, CW
Lewis, SA
Garulacan, LA
Soler, AP
Mullin, JM
[J]. JOURNAL OF MEMBRANE BIOLOGY, 1998, 161 (03) : 263 - 274
[56] LONG-TERM EFFECTS OF TUMOR-NECROSIS-FACTOR ON LLC-PK(1) TRANSEPITHELIAL RESISTANCE
MARANO, CW
LAUGHLIN, KV
RUSSO, LM
SOLER, AP
MULLIN, JM
[J]. JOURNAL OF CELLULAR PHYSIOLOGY, 1993, 157 (03) : 519 - 527
[57] Cytokine-induced increases in endothelial permeability occur after adhesion molecule expression
Marcus, BC
Wyble, CW
Hynes, KL
Gewertz, BL
[J]. SURGERY, 1996, 120 (02) : 411 - 417
[58] A peculiar internalization of claudins, tight junction-specific adhesion molecules, during the intercellular movement of epithelial cells
Matsuda, M
Kubo, A
Furuse, M
Tsukita, S
[J]. JOURNAL OF CELL SCIENCE, 2004, 117 (07) : 1247 - 1257
[59] Role of IL-10 in hepatocyte tight junction alteration in mouse model of experimental colitis
Mazzon, E
Puzzolo, D
Caputi, AP
Cuzzocrea, S
[J]. MOLECULAR MEDICINE, 2002, 8 (07) : 353 - 366
[60] McCarthy KM, 1996, J CELL SCI, V109, P2287

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