An Au nanoparticle/bisbipyridinium cyclophane-functionalized ion sensitive field-effect transistor for the sensing of adrenaline

被引：72

作者：

Kharitonov, AB ^{[1
]}

Shipway, AN ^{[1
]}

Willner, I ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Inst Chem, IL-91904 Jerusalem, Israel

来源：

ANALYTICAL CHEMISTRY | 1999年 / 71卷 / 23期

关键词：

D O I：

10.1021/ac990997s

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A film consisting of polyethyleneimine (PEI), An nanoparticles (12 +/- 1 nm) and coadsorbed cyclobis(paraquat-p-phenylene) (1) was assembled as a sensing interface on the Al2O3 insulating layer of an ion-sensitive field-effect transistor (ISFET). Adrenaline (2) was sensed by the functionalized ISFET with a detection limit of 1 x 10(-6) M. The sensing ability of the nanostructured device for the analysis of adrenaline originates from the preconcentration of the analyte in the cyclophane by pi-pi donor-acceptor interactions. Analysis of adrenaline is accomplished by the measurement of the source-drain current, I-sd, or by the gate-source voltage, V-gs. The sensing device is reusable (at least 100 cycles) and exhibits high stability.

引用

页码：5441 / 5443

页数：3

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