Asymmetric aldol reactions in poly(ethylene glycol) catalyzed by L-proline

被引：98

作者：

Chandrasekhar, S ^{[1
]}

Narsihmulu, C ^{[1
]}

Reddy, NR ^{[1
]}

Sultana, SS ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 23期

关键词：

asymmetric aldol reaction; L-proline; PEG; reusability;

D O I：

10.1016/j.tetlet.2004.03.116

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A rapid L-proline catalyzed direct aldol reaction between various aldehydes and acetone was achieved using PEG as the solvent with comparable enantioselectivities and yields to those obtained in other solvents. Recycling the catalyst and solvent (PEG) was possible 10 times without loss of activity. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：4581 / 4582

页数：2

共 23 条

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