Progress in boronic acid-based fluorescent glucose sensors

被引：205

作者：

Fang, H ^{[1
]}

Kaur, G ^{[1
]}

Wang, BH ^{[1
]}

机构：

[1] Georgia State Univ, Dept Chem, Atlanta, GA 30303 USA

来源：

JOURNAL OF FLUORESCENCE | 2004年 / 14卷 / 05期

关键词：

glucose monitoring; boronic acid; fluorescence sensor;

D O I：

10.1023/B:JOFL.0000039336.51399.3b

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Effective management of diabetes relies on the frequent monitoring of blood glucose concentrations. The current approach of blood sampling and glucose concentration determination in vitro presents many problems. Therefore, there is a drive for the development of non-invasive and continuous monitoring of glucose concentrations. The use of implanted glucose fluorescent sensors represents a promising approach. Due to its strong interaction with diol moieties, the boronic acid group often plays a critical role in the design of such glucose sensors. This paper reviews the progress in this area during the last ten years.

引用

页码：481 / 489

页数：9

共 44 条

[11] Monoboronic acid sensor that displays anomalous fluorescence sensitivity to glucose [J].

Cao, HS ;

Diaz, DI ;

DiCesare, N ;

Lakowicz, JR ;

Heagy, MD .

ORGANIC LETTERS, 2002, 4 (09) :1503-1505

[12]

Daniloff G Y, 1999, Diabetes Technol Ther, V1, P261, DOI 10.1089/152091599317170

[13] Wavelength-ratiometric probes for saccharides based on donor-acceptor diphenylpolyenes [J].

Di Cesare, N ;

Lakowicz, JR .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2001, 143 (01) :39-47

[14] Spectral properties of fluorophores combining the boronic acid group with electron donor or withdrawing groups. Implication in the development of fluorescence probes for saccharides [J].

DiCesare, N ;

Lakowicz, JR .

JOURNAL OF PHYSICAL CHEMISTRY A, 2001, 105 (28) :6834-6840

[15]

DiCesare N, 2002, TETRAHEDRON LETT, V43, P2615, DOI 10.1016/s0040-4039(02)00312-x

[16] Charge transfer fluorescent probes using boronic acids for monosaccharide signaling [J].

DiCesare, N ;

Lakowicz, JR .

JOURNAL OF BIOMEDICAL OPTICS, 2002, 7 (04) :538-545

[17] A new highly fluorescent probe for monosaccharides based on a donor-acceptor diphenyloxazole [J].

DiCesare, N ;

Lakowicz, JR .

CHEMICAL COMMUNICATIONS, 2001, (19) :2022-2023

[18] A new glucose-selective fluorescent bisboronic acid.: First report of strong α-furanose complexation in aqueous solution at physiological pH [J].

Eggert, H ;

Frederiksen, J ;

Morin, C ;

Norrild, JC .

JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (11) :3846-3852

[19] New boronic acid fluorescent reporter compounds. 2. A naphthalene-based on-off sensor functional at physiological pH [J].

Gao, XM ;

Zhang, YL ;

Wang, BH .

ORGANIC LETTERS, 2003, 5 (24) :4615-4618

[20] DEVELOPMENT OF THE IMPLANTABLE GLUCOSE SENSOR - WHAT ARE THE PROSPECTS AND WHY IS IT TAKING SO LONG [J].

GOUGH, DA ;

ARMOUR, JC .

DIABETES, 1995, 44 (09) :1005-1009

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