Are copper, zinc and selenium in erythrocytes valuable biological indexes of nutrition and pathology?

被引:38
作者
Vitoux, D
Arnaud, J
Chappuis, P
机构
[1] Hop St Louis, Serv Biochim A1, Biochem Lab, F-75475 Paris 10, France
[2] Grenoble Hosp, Biochem Lab C, F-38043 Grenoble, France
[3] Hop Lariboisiere, Biochem & Mol Biol Lab, F-75475 Paris 10, France
关键词
copper; zinc; selenium; erythrocytes;
D O I
10.1016/S0946-672X(99)80001-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The real significance of the level of trace elements copper, zinc and selenium in erythrocytes is still a matter of debate. This review is an evaluation of the potential value of copper, zinc and selenium in red blood cells in physiology, nutrition and pathology, taking into account the other commonly used indices and the analytical difficulty encountered for erythrocyte determinations. The main analytical methods and reference values in erythrocytes are also presented. The literature of the last 3 decades was analyzed. On the basis of these papers, the role of erythrocyte copper in various pathologies should be re-investigated, especially when they include inflammatory processes or hormonal changes. The main interest of zinc determination in red blood cells concerns thyroid pathology. In general, the value of selenium in erythrocytes agrees with selenium in serum and its determination is often unnecessary.
引用
收藏
页码:113 / 128
页数:16
相关论文
共 151 条
[111]   SELENIUM DEPLETION IN PATIENTS ON HOME PARENTERAL-NUTRITION - THE EFFECT OF SELENIUM SUPPLEMENTATION [J].
RANNEM, T ;
LADEFOGED, K ;
HYLANDER, E ;
HEGNHOJ, J ;
JARNUM, S .
BIOLOGICAL TRACE ELEMENT RESEARCH, 1993, 39 (01) :81-90
[112]   MAGNESIUM, ZINC AND COPPER IN PLASMA AND BLOOD CELLULAR-COMPONENTS IN CHILDREN WITH IDDM [J].
ROHN, RD ;
PLEBAN, P ;
JENKINS, LL .
CLINICA CHIMICA ACTA, 1993, 215 (01) :21-28
[113]  
ROMERO RA, 1990, TRACE ELEM MED, V7, P176
[114]   MERCURY AND SELENIUM DISTRIBUTION IN A DEFINED AREA AND IN ITS POPULATION [J].
ROSSI, LC ;
SANTARONI, G ;
CLEMENTE, GF .
ARCHIVES OF ENVIRONMENTAL HEALTH, 1976, 31 (03) :160-165
[115]   VARIATIONS IN MAGNESIUM AND ZINC IN HYPERTENSIVE PATIENTS RECEIVING DIFFERENT TREATMENTS [J].
RUBIOLUENGO, MA ;
MALDONADOMARTIN, A ;
GILEXTREMERA, B ;
GONZALEZGOMEZ, L ;
DELCASTILLO, JDL .
AMERICAN JOURNAL OF HYPERTENSION, 1995, 8 (07) :689-695
[116]  
RUKGAUER M, 1995, J TRACE ELEM MED BIO, V9, P130
[117]   ERYTHROCYTES, ERYTHROCYTE-MEMBRANES, NEUTROPHILS AND PLATELETS AS BIOPSY MATERIALS FOR THE ASSESSMENT OF ZINC STATUS IN HUMANS [J].
RUZ, M ;
CAVAN, KR ;
BETTGER, WJ ;
GIBSON, RS .
BRITISH JOURNAL OF NUTRITION, 1992, 68 (02) :515-527
[118]   A CASE OF MENKES SYNDROME WITH CATARACTS [J].
SAKANO, T ;
OKUDA, N ;
YOSHIMITSU, K ;
HATANO, S ;
NISHI, Y ;
TANAKA, T ;
USUI, T .
EUROPEAN JOURNAL OF PEDIATRICS, 1982, 138 (04) :357-358
[119]   ZINC-METABOLISM IN HYPOTHYROIDISM [J].
SANER, G ;
SAVASAN, S ;
SAKA, N .
LANCET, 1992, 340 (8816) :432-433
[120]   MATERNAL ZINC AND INTRAUTERINE GROWTH-RETARDATION [J].
SIMMER, K ;
THOMPSON, RPH .
CLINICAL SCIENCE, 1985, 68 (04) :395-399