The biosynthesis of adenosylcobalamin (vitamin B12)

被引：345

作者：

Warren, MJ

Raux, E

Schubert, HL

Escalante-Semerena, JC

机构：

[1] Univ London, Queen Mary, Sch Biol Sci, London E1 4NS, England

[2] Univ Utah, Dept Biochem, Salt Lake City, UT 84132 USA

[3] Univ Wisconsin, Dept Bacteriol, Madison, WI 53706 USA

来源：

NATURAL PRODUCT REPORTS | 2002年 / 19卷 / 04期

关键词：

D O I：

10.1039/B108967F

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Vitamin B-12, or cobalamin, is one of the most structurally complex small molecules made in Nature. Major progress has been made over the past decade in understanding how this synthesis is accomplished. This review covers some of the most important findings that have been made and provides the reader with a complete description of the transformation of uroporphyrinogen III into adenosylcobalamin (AdoCbl). 183 references are cited.

引用

页码：390 / 412

页数：23

共 183 条

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