Two dimensional PNA/DNA arrays: estimating the helicity of unusual nucleic acid polymers

被引：42

作者：

Lukeman, PS ^{[1
]}

Mittal, AC ^{[1
]}

Seeman, NC ^{[1
]}

机构：

[1] NYU, Dept Chem, New York, NY 10003 USA

来源：

CHEMICAL COMMUNICATIONS | 2004年 / 15期

关键词：

D O I：

10.1039/b401103a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We extend the generality of nucleic acid-based structural nanotechnology by incorporating non-natural nucleic acids into a DNA double crossover (DX) molecule; visualizing two-dimensional arrays of these DX molecules by Atomic Force Microscopy (AFM) enables us to measure the helical repeat of any heteroduplex sequence capable of forming the outer arms of a DX.

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页码：1694 / 1695

页数：2

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