Is haplotype block identification useful for association mapping studies?

被引：10

作者：

Zhai, WW ^{[1
]}

Todd, MJ ^{[1
]}

Nielsen, R ^{[1
]}

机构：

[1] Cornell Univ, Dept Biol Stat & Computat Biol, Ithaca, NY 14853 USA

来源：

GENETIC EPIDEMIOLOGY | 2004年 / 27卷 / 01期

关键词：

D O I：

10.1002/gepi.20014

中图分类号：

Q3 [遗传学];

学科分类号：

071007 [遗传学]; 090102 [作物遗传育种];

摘要：

引用

收藏

页码：80 / 83

页数：4

相关论文

共 17 条

[1]

Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans [J].

Carlson, CS ;

Eberle, MA ;

Rieder, MJ ;

Smith, JD ;

Kruglyak, L ;

Nickerson, DA .

NATURE GENETICS, 2003, 33 (04) :518-521

[2]

High-resolution patterns of meiotic recombination across the human major histocompatibility complex [J].

Cullen, M ;

Perfetto, SP ;

Klitz, W ;

Nelson, G ;

Carrington, M .

AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 71 (04) :759-776

[3]

High-resolution haplotype structure in the human genome [J].

Daly, MJ ;

Rioux, JD ;

Schaffner, SE ;

Hudson, TJ ;

Lander, ES .

NATURE GENETICS, 2001, 29 (02) :229-232

[4]

The structure of haplotype blocks in the human genome [J].

Gabriel, SB ;

Schaffner, SF ;

Nguyen, H ;

Moore, JM ;

Roy, J ;

Blumenstiel, B ;

Higgins, J ;

DeFelice, M ;

Lochner, A ;

Faggart, M ;

Liu-Cordero, SN ;

Rotimi, C ;

Adeyemo, A ;

Cooper, R ;

Ward, R ;

Lander, ES ;

Daly, MJ ;

Altshuler, D .

SCIENCE, 2002, 296 (5576) :2225-2229

[5]

Generating samples under a Wright-Fisher neutral model of genetic variation [J].

Hudson, RR .

BIOINFORMATICS, 2002, 18 (02) :337-338

[6]

Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex [J].

Jeffreys, AJ ;

Kauppi, L ;

Neumann, R .

NATURE GENETICS, 2001, 29 (02) :217-222

[7]

Haplotype tagging for the identification of common disease genes [J].

Johnson, GCL ;

Esposito, L ;

Barratt, BJ ;

Smith, AN ;

Heward, J ;

Di Genova, G ;

Ueda, H ;

Cordell, HJ ;

Eaves, IA ;

Dudbridge, F ;

Twells, RCJ ;

Payne, F ;

Hughes, W ;

Nutland, S ;

Stevens, H ;

Carr, P ;

Tuomilehto-Wolf, E ;

Tuomilehto, J ;

Gough, SCL ;

Clayton, DG ;

Todd, JA .

NATURE GENETICS, 2001, 29 (02) :233-237

[8]

Issues concerning association studies for fine mapping a susceptibility gene for a complex disease [J].

Kaplan, N ;

Morris, R .

GENETIC EPIDEMIOLOGY, 2001, 20 (04) :432-457

[9]

Prospects for whole-genome linkage disequilibrium mapping of common disease genes [J].

Kruglyak, L .

NATURE GENETICS, 1999, 22 (02) :139-144

[10]

Makova KD, 2001, GENETICS, V158, P1253