QTL analysis of trabecular bone in BXD F2 and RI mice

被引：15

作者：

Bower, Abbey L.

Lang, Dean H.

Vogler, George P.

Vandenbergh, David J.

Blizard, David A.

Stout, Joseph T.

McClearn, Gerald E.

Sharkey, Neil A.

机构：

[1] Penn State Univ, Biomech Lab, University Pk, PA 16802 USA

[2] Penn State Univ, Dept Kinesiol, Coll Hlth & Human Dev, University Pk, PA 16802 USA

[3] Penn State Univ, Ctr Dev & Hlth Genet, University Pk, PA 16802 USA

[4] Penn State Univ, Coll Hlth & Human Dev, Dept Biobehav Hlth, University Pk, PA 16802 USA

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2006年 / 21卷 / 08期

关键词：

quantitative trait loci; rodent model; osteoporosis; mu CT; trabecular bone;

D O I：

10.1359/JBMR.060501

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A sample of 693 mice was used to identify regions of the mouse genome associated with trabecular bone architecture as measured using mu CT. QTLs for bone in the proximal tibial metaphysis were identified on several chromosomes indicating regions containing genes that regulate properties of trabecular bone.

引用

收藏

页码：1267 / 1275

页数：9

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