SENTRA, a database of signal transduction proteins

被引：7

作者：

D'Souza, M

Romine, MF

Maltsev, N

机构：

[1] Argonne Natl Lab, Div Math & Comp Sci, Argonne, IL 60439 USA

[2] Pacific NW Lab, Environm Microbiol Grp, Richland, WA 99352 USA

来源：

NUCLEIC ACIDS RESEARCH | 2000年 / 28卷 / 01期

关键词：

D O I：

10.1093/nar/28.1.335

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

SENTRA, available via URL http://wit.mcs.anl.gov/WIT2/Sentra/, is a database of proteins associated with,microbial signal transduction, The database currently includes the classical two-component signal transduction pathway proteins and methyl-accepting chemotaxis proteins, but will be expanded to also include other classes of signal transduction systems that are modulated by phosphorylation or methylation reactions. Although the majority of database-entries are from prokaryotic systems, eukaroytic proteins with bacterial-like signal transduction domains are also included. Currently SENTRA contains signal transduction proteins in 34 complete and almost completely sequenced prokaryotic genomes; as well as sequences from 243 organisms available in public databases (SWISS-PROT and EMBL). The analysis was carried out within the framework of the WIT2 system, which is designed and implemented to support genetic sequence analysis and comparative analysis of sequenced genomes.

引用

页码：335 / 336

页数：2

共 9 条

[1]

ALTSCHUL SF, 1990, J MOL BIOL, V215, P403, DOI 10.1006/jmbi.1990.9999

[2]

Bateman A, 2004, NUCLEIC ACIDS RES, V32, pD138, DOI [10.1093/nar/gkp985, 10.1093/nar/gkh121, 10.1093/nar/gkr1065]

[3] Pfam 3.1: 1313 multiple alignments and profile HMMs match the majority of proteins [J].

Bateman, A ;

Birney, E ;

Durbin, R ;

Eddy, SR ;

Finn, RD ;

Sonnhammer, ELL .

NUCLEIC ACIDS RESEARCH, 1999, 27 (01) :260-262

[4] A flexible motif search technique based on generalized profiles [J].

Bucher, P ;

Karplus, K ;

Moeri, N ;

Hofmann, K .

COMPUTERS & CHEMISTRY, 1996, 20 (01) :3-23

[5] SOSUI: classification and secondary structure prediction system for membrane proteins [J].

Hirokawa, T ;

Boon-Chieng, S ;

Mitaku, S .

BIOINFORMATICS, 1998, 14 (04) :378-379

[6] The PROSITE database, its status in 1999 [J].

Hofmann, K ;

Bucher, P ;

Falquet, L ;

Bairoch, A .

NUCLEIC ACIDS RESEARCH, 1999, 27 (01) :215-219

[7] The use of gene clusters to infer functional coupling [J].

Overbeek, R ;

Fonstein, M ;

D'Souza, M ;

Pusch, GD ;

Maltsev, N .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (06) :2896-2901

[8]

OVERBEEK R, 1999, MOL BIOL DATABASES, P158

[9]

Parkinson JS, 1995, 2 COMPONENT SIGNAL T, P9

← 1 →