The synthesis of enantiomerically pure disubstituted aziridines and N-alkoxy aziridines

被引：28

作者：

Hanessian, S ^{[1
]}

Cantin, LD ^{[1
]}

机构：

[1] Univ Montreal, Dept Chem, Montreal, PQ H3C 3J7, Canada

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 06期

关键词：

D O I：

10.1016/S0040-4039(99)02211-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The addition of a chloroallyl phosphonamide anion to oximes has allowed the preparation of a variety of cis-disubstituted N-alkoxy aziridines in enantiomerically pure form. Oxidative cleavage of the chiral auxiliary followed by derivatization of the products has allowed the preparation of enantiopure N-alkoxy aziridines. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：787 / 790

页数：4

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